Ooh là là ♥

hotboysofficial:

how to subtly approach your crush

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  • me: my arm hurts
  • mom: it's the computer
  • me: my eyes hurt
  • mom: it's the computer
  • me: i have a nosebleed
  • mom: it's the computer
  • me: i have a fever
  • mom: are you sure it's not the heat from the computer
  • me: im pregnant
  • mom: it's the computer
  • me: i fell down the stairs & hurt my tailbone
  • mom: the computer pushed you didnt it

X-linked Recessive Diseases List
  • Alport’s Sd: "hereditary nephritis", type IV collagen deficiency, alternating thickening & thinning of GBM, COL4A5 mutation, hearing loss, ocular abnormalities (lens & cornea), hematuria (gross or micro) since childhood.
  • Bruton’s Agammaglobulinemia: btk gene defect, no mature B cells or plasma cells, low lymphoid tissue, hepatitis, enterovirus infxs, first 6 months protected by maternal ab (no symptoms)
  • Becker’s Muscular Dystrophy: altered dystrophin gene, later onset than Duchene's, slow progression, relatively normal life span, less severe, rare cardiac involvement.
  • Chronic Granulomatose Disease (CGD): NAPDH oxidase deficiency, recurrent catalase (+) infxs, nitroblue tetrazolium test negative (yellow)
  • Congenital Aqueductus Stenosis: MCC of congenital obstructive hydrocephalus.
  • Color blindness (red-green): can't distinguish shades of red and green (usually blue-green)
  • Duchene’s muscular Dystrophy: dystrophin gene mutation (Xp21), absent dystrophyn protein, MC & severe of muscular dystrophies, normal until 5yo, short life span (<30yo), progressive muscle weakness, calf pseudohypertrophy, <3 failure, arrythmias, respiratory insufficiency and infxs (decreased mucociliary clearence). Pneumonias CC of death.
  • Fabry’s Disease: alpha Galactosidase A, Ceramide trihexose accumulation, angiokeratomas, renal failure, peripheral neuropathy.
  • Glucose 6-P Dehydrogenase (G6PD) Deficiency: chronic hemolytic anemia, MCC of enzymatic deficiency HA, Heinz bodies, bite cells. Triggers are infections, drugs (antimalarial), fava beans
  • Hemophilia A & B: factor VIII & IX deficiency respectively. PTT prolongation.
  • Hunter Disease: iduronate sulfatase deficiency, heparan sulfate accumulation, no corneal clouding, aggressive behaviour.
  • Inherited Nephrogenic Diabetes Insipidus: V2 receptors in collecting duct don't respond to ADH.
  • Lesch-Nyhan Sd: HGPRT1 deficiency, spastic cerebral palsy, self-mutilation, hyperuricemia, oral crystals in diapers, early death.
  • Menkes Disease: ATP7A gene mutation (copper efflux protein), Cu+ is lysil oxidase cofactor, Cu+ accumulates in intestine & kidneys; deficient in other tissues = deficient collagen cross linking; steely 'kinky' hair, MR, arterial tortuosity, hypotonia.
  • Ornithine Transcarbamoylase Deficiency: urea cycle, orotic aciduria + hyperammonemia (no megaloblastic anemia), orotic acid accumulation, increased glutamine . Cerebral edema, lethargy, vomiting, hyperventilation, convulsions, coma, death.
  • SCID: IL-receptor, Gamma chain deficiency
  • Wiskott Aldrich Sd: combined partial B & T immunodeficiency, IgM deficiency, thrombocytopenia, eczema.

the-wolf-and-moon:

I Felt Very Small

the-wolf-and-moon:

I Felt Very Small

ragincontagion:

Patterned injuries on a pedestrian who was struck by a truck. Note the the level of the markings correlate with the height of the grill on the truck. These markings are made by hematoma, which is a collection of blood outside of vessels in tissue.

ragincontagion:

Patterned injuries on a pedestrian who was struck by a truck. Note the the level of the markings correlate with the height of the grill on the truck. These markings are made by hematoma, which is a collection of blood outside of vessels in tissue.

aroxia:

swagginmun:

nefertsukia:

disneyprincessalexia:

thehufflepufffromgallifrey:

I must have watched Shrek about fifty times, but only last night did I notice that Lord Faarquad pops a boner when the mirror shows him Fiona.

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Christ on a bike!

i cAN’T BRHREATEH

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I made the same face the mirror did


Despite the funky #weather situation there&#8217;s not reason why we shouldn&#8217;t be #happy &#8230;enough sadness in the world already

Despite the funky #weather situation there’s not reason why we shouldn’t be #happy …enough sadness in the world already

fuckyeahfluiddynamics:

Wingtip vortices are a result of the finite length of a wing. Airplanes generate lift by having low-pressure air travelling over the top of the wing and higher pressure air along the bottom. If the wing were infinite, the two flows would remain separate. Instead, the high-pressure air from under the wing sneaks around the wingtip to reach the lower pressure region. This creates the vorticity that trails behind the aircraft. I was first introduced to the concept of wingtip vortices in my junior year during introductory fluid dynamics. As I recall, the concept was utterly bizarre and so difficult to wrap our heads around that everyone, including the TA, had trouble figuring out which way the vortices were supposed to spin. A few good photos and videos would have helped, I’m sure. (Photo credits: U.S. Coast Guard, S. Morris, Nat. Geo/BBC2)

sassykardashian:

my heart says yes but my bank balance says no

(Source: sassykardashian)


(Source: )

(Source: naughty-couples)